反应详情

温度

0 °C

4-(2-Bromo-acetyl)-benzenesulfonyl chloride (150 mg, 0.17 mmol) was dissolved in 4 mL of dry dichloromethane. To this solution at 0° C., was added triethylamine (0.03 mL, 0.2 mmol), followed by cyclopentylamine (0.2 mmol, 0.011 g). Reaction mixture was stirred at 0° C. for 15 minutes and then quenched with H2O. The reaction mixture was extracted with H2O. The organic phase was isolated, dried over MgSO4 and evaporated. It was used in the next step without any further purification.

1. customReaction mixture
2. customquenched with H2O
3. extractionThe reaction mixture was extracted with H2O
4. customThe organic phase was isolated
5. dry with materialdried over MgSO4
6. customevaporated
7. customIt was used in the next step without any further purification