p-Toluidine → 3-Pyridinamine, N-(4-methylphenyl)-

HRID 739665노트

반응식

HRID 739665 반응식
Brc1cccnc1.Cc1ccc(N)cc1>CC(C)c1cc(C(C)C)c(-c2ccccc2[P](C(C)(C)C)(C(C)(C)C)->[Pd]2(<-[NH2]c3ccccc3-c3cccc[c]32)[O]S(=O)(=O)C(F)(F)F)c(C(C)C)c1.CCOC(=O)c1cnoc1.CN(C)C(=NC(C)(C)C)N(C)C.CS(C)=O>Cc1ccc(Nc2cccnc2)cc1

참가 물질

7

반응물 2

HCID 7813p-ToluidineHCID 122863-Bromopyridine

생성물 1

HCID 6035893-Pyridinamine, N-(4-methylphenyl)-수율 2.398%

시약·촉매·용매 4

HCID 35715812-tert-Butyl-1,1,3,3-tetramethylguanidine시약HCID 15590757Ethyl 1,2-oxazole-4-carboxylate시약HCID 178439023HCID 178439023, 화합물촉매HCID 679Dimethyl Sulfoxide용매5회

반응 조건

온도
60 °C

실험 절차

These solutions were added to a 384- well source plate (80 µL per well). The Mosquito HTS liquid handling robot was used to dose each of these solutions (200 nL each) into a 1536-well plate.

후처리

  1. addition기록된 절차가 없습니다

출처 및 근거

ORD 기록
ord-464bcf4bc517470d94d957d4c2e745fc
출처 데이터셋
Ahneman

반응 노트

불러오는 중…