p-Toluidine → 3-Pyridinamine, N-(4-methylphenyl)-

HRID 741224노트

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HRID 741224 반응식
Cc1ccc(N)cc1.Clc1cccnc1>CCN=P(N=P(N(C)C)(N(C)C)N(C)C)(N(C)C)N(C)C.COc1ccc(OC)c([P](C(C)(C)C)(C(C)(C)C)->[Pd]2(<-[NH2]c3ccccc3-c3cccc[c]32)[O]S(=O)(=O)C(F)(F)F)c1-c1c(C(C)C)cc(C(C)C)cc1C(C)C.CS(C)=O.c1ccc(CN(Cc2ccccc2)c2ccno2)cc1>Cc1ccc(Nc2cccnc2)cc1

참가 물질

7

반응물 2

HCID 7813p-ToluidineHCID 122873-Chloropyridine

생성물 1

HCID 6035893-Pyridinamine, N-(4-methylphenyl)-수율 13.534%

시약·촉매·용매 4

HCID 33931062,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramine시약HCID 178420340HCID 178420340, 화합물시약HCID 178492620HCID 178492620, 화합물촉매HCID 679Dimethyl Sulfoxide용매5회

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온도
60 °C

실험 절차

These solutions were added to a 384- well source plate (80 µL per well). The Mosquito HTS liquid handling robot was used to dose each of these solutions (200 nL each) into a 1536-well plate.

후처리

  1. addition기록된 절차가 없습니다

출처 및 근거

ORD 기록
ord-a4956a2542b94ea382cf266556efe8f2
출처 데이터셋
Ahneman

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