反应详情

温度

200 °C

2-Pentanone (8.61 g, 10.6 ml, 0.1 mol), glycerol (92.09 g, 73.7 ml, 1 mol), and 10% Pd/C (5 wt %, 0.43 g) are charged to a Parr reactor, purged with nitrogen, heated to 200° C. with stirring and run at 1000 psi of hydrogen for 4 hrs. GC analysis reveals 92% conversion of 2-pentanone and shows selectivity to 3-sec-pentoxy-1,2-propanediol and 2-sec-pentoxy-1,3-propanediol (76.2%, isomer ratio 32.1), 1,3-di-sec-pentoxy-2-propanol (6.1%), 2-pentanol (6.9%), 4-hydroxymethyl-2-methyl-2-propyl-1,3-dioxolane (cyclic ketal) (6.7%).

1. custompurged with nitrogen