反应详情

The title compound was prepared from ax-2-hydroxymethylquinolizidine (D4) and indole-3-carboxylic acid chloride using the method of Example 1. The product was purified by chromatography on neutral alumina eluting with ethyl acetate, followed by crystallisation from ether/pentane, to give the title compound (E9a) as a white solid mp 156°-157° C.

1. customThe product was purified by chromatography on neutral alumina eluting with ethyl acetate
2. customfollowed by crystallisation from ether/pentane