Hydrochloric Acid → HCID 67740802, compound

HRID 741719Notes

Reaction equation

HRID 741719 reaction equation
C([NH:8][C@H:9]([C:17]([NH:19][C:20]1[N:21]([CH3:25])[CH:22]=[CH:23][N:24]=1)=[O:18])[CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)(OC(C)(C)C)=O.[ClH:26]>>[ClH:26].[ClH:26].[CH3:25][N:21]1[CH:22]=[CH:23][N:24]=[C:20]1[NH:19][C:17](=[O:18])[C@H:9]([CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[NH2:8]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 22865214HCID 22865214, compound

Product 1

HCID 67740802HCID 67740802, compoundYield 66.3%

Procedure

2-(N-Boc-phenylalanyl)amino-1-methylimidazole (0.3 g) was dissolved in conc. hydrochloric acid (10 ml), and the solution was stirred at room temperature for 30 minutes. The solvent was evaporated, and the precipitated colorless powder was separated by filtration using diethyl ether to give the title compound (0.23 g, 66.3%).

Workup

  1. customThe solvent was evaporated
  2. customthe precipitated colorless powder was separated by filtration

Sources & evidence

ORD record
ord-b77fa197fb4547c2b81fe0eed6eb57b0
Source dataset
uspto-grants-1996_09
Patent number
US05552427

Reaction notes

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