Sodium Perchlorate → HCID 10424614, compound

HRID 742457Notes

Reaction equation

HRID 742457 reaction equation
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].C[O:7][C:8]1[C:13]2=[CH:14][C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][N+:20]=3[CH:21]=[C:12]2[CH:11]=[CH:10][CH:9]=1.Cl([O-])(=O)(=O)=O.[Na+]>Br>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[OH:7][C:8]1[C:13]2=[CH:14][C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][N+:20]=3[CH:21]=[C:12]2[CH:11]=[CH:10][CH:9]=1

Participants

4

Reactant 2

HCID 522606Sodium PerchlorateHCID 15186219HCID 15186219, compound

Product 1

HCID 10424614HCID 10424614, compoundYield 75.9%

Reagents, catalysts & solvents 1

HCID 260Hydrogen BromideSolvent

Conditions

Temperature
100 °C

Procedure

A mixture of 4 g of 10-methoxybenzo[b]quinolizinium perchlorate in 50 mL of 48% HBr was heated at 100° C. for 20 h, cooled to room temperature, and the resulting mixture was poured into 100 mL of 50% sodium perchlorate solution and stirred for 5 min. The precipitate was filtered, washed with ice-water, ether, ethyl acetate and air dried to afford 2.9 g of 10-hydroxybenzo[b]quinolizinium perchlorate, (Formula II: R1 =R2 =H; R7 =10--OH; X- =ClO4-) m.p. 218°-229° C. (d).

Workup

  1. temperaturecooled to room temperature
  2. filtrationThe precipitate was filtered
  3. washwashed with ice-water, ether, ethyl acetate and air
  4. customdried

Sources & evidence

ORD record
ord-d38854972a4e445887e9e91f3eeffa78
Source dataset
uspto-grants-1996_09
Patent number
US05554620

Reaction notes

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