HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 1-(Bromomethyl)-4-(trifluoromethyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 4-(Trifluoromethyl)benzenemethanol | HCID 67684 | — |
| Product | 1-(Bromomethyl)-4-(trifluoromethyl)benzene | HCID 123062 | — |
Reaction Steps
A mixture of 5.5 g of p-trifluoromethyl-benzyl alcohol in 50 mL of 48% HBr was heated on a steam-bath for 6 h with stirring, and cooled. Water (100 mL) was added to the above mixture, and the aqueous layer was extracted with ether, and the organic layer was concentrated in vacuo to afford 4.8 g of p-trifluoromethyl-benzyl bromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05554620 |
| Source dataset | uspto-grants-1996_09 |
| ORD ID | ord-4eb45ddb9be34dabbad329cb9fd7f051 |
| Source note | uspto-grants-1996_09 |