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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 742980Generated: October 29, 2026

HCID 19423444, compound → HCID 19027729, compound

https://huagongshe.com/reaction/742980

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 19423444HCID 19423444—
SolventHydrochloric AcidHCID 313—
ProductHCID 19027729HCID 19027729168.2%

Reaction Steps

5-Acetylamino-1-{3-[4-(3-chlorophenyl)-1-piperazinyl]propyl}-3,4-dihydrocarbostyril (800 mg) was dissolved in 20 ml of 6 N hydrochloric acid, and the mixture was heated under reflux for 1 hour. The reaction mixture was concentrated under reduced pressure and the residue was recrystallized from ethanol to give 480 mg of 5-amino-1-{3-[4-(3-chlorophenyl)-1-piperazinyl]propyl}-3,4-dihydrocarbostyril dihydrochloride as a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05556857
Source datasetuspto-grants-1996_09
ORD IDord-ad3b480fff13480c941b0c5c1944133d
Source noteuspto-grants-1996_09