2-Bromoethanol → HCID 19423621, compound

HRID 743060Notes

Reaction equation

HRID 743060 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([N:7]2[CH:16]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[NH:9][C:8]2=[O:23])[CH2:3][CH2:2]1.[CH2:24](Br)[CH2:25][OH:26]>>[OH:26][CH2:25][CH2:24][N:1]1[CH2:2][CH2:3][CH:4]([N:7]2[CH:16]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[NH:9][C:8]2=[O:23])[CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 108982-BromoethanolHCID 15896329HCID 15896329, compound

Product 1

HCID 19423621HCID 19423621, compound

Procedure

In similar way as in Preparation Example 31, the title compound was synthesized from 3-(piperidin-4-yl)-4-phenyl-3,4-dihydro-2(1H)-quinazolinone and ethylene bromohydrin.

Workup

  1. customIn similar way as in Preparation Example 31

Sources & evidence

ORD record
ord-5401d7f1a11d43fb8772c9e34c06b050
Source dataset
uspto-grants-1996_09
Patent number
US05556860

Reaction notes

Loading…