反应详情

Following a procedure similar to that described in Example 1(a), 634 mg of 2-[4-(2-cyanophenyl)butyl]phenol (prepared as described in Preparation 11), 283 mg of potassium t-butoxide and 345 mg of epibromohydrin were reacted in 6 ml of dimethylacetamide. The crude product, extracted as described in Example 1, was purified as described in Example 1, to give 690 mg (yield 89%) of the title compound as an oil.

1. extractionThe crude product, extracted
2. customwas purified