Dimethylamine → HCID 10595788, compound

HRID 743203Notes

Reaction equation

HRID 743203 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][CH2:10][CH2:11][C:12]2[CH:22]=[CH:21][CH:20]=[CH:19][C:13]=2[O:14][CH2:15][CH:16]2[CH2:18][O:17]2)[CH:5]=[CH:6][CH:7]=1.[CH3:23][NH:24][CH3:25]>O1CCCC1>[CH3:23][N:24]([CH3:25])[CH2:18][CH:16]([OH:17])[CH2:15][O:14][C:13]1[CH:19]=[CH:20][CH:21]=[CH:22][C:12]=1[CH2:11][CH2:10][CH2:9][CH2:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([CH3:1])[CH:3]=1

Participants

4

Reactant 2

HCID 674DimethylamineHCID 10732721HCID 10732721, compound

Product 1

HCID 10595788HCID 10595788, compoundYield 59%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following a procedure similar to that described in Example 1(b), 1.83 g of 2-{2-[4-(3-methylphenyl)butyl]phenoxymethyl}oxirane [prepared as described in step (a) above] dissolved in 20 ml of tetrahydrofuran were treated with 4 ml of 50% by volume aqueous dimethylamine. The crude product thus obtained was purified as described in Example 1(b), to give 1.25 g (yield 59%) of the title compound as a colorless oil.

Workup

  1. customThe crude product thus obtained
  2. customwas purified

Sources & evidence

ORD record
ord-56a8e65052c843a68b8d00a051964acb
Source dataset
uspto-grants-1996_09
Patent number
US05556864

Reaction notes

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