Dimethylamine → HCID 54340814, compound

Participants

Reaction Steps

Following a procedure similar to that described in Example 1(b), a solution of 328 mg of 2-{2-[4-(2-benzyloxyphenyl)-1-buten-1-yl]phenoxymethyl}oxirane [prepared as described in step (a) above] dissolved in 5 ml of tetrahydrofuran was treated with 3 ml of 50% by volume aqueous dimethylamine. The crude product was purified as described in Example 1(b), to give 3-dimethylamino-1-{2-[4-(2-benzyloxyphenyl)-1-buten-1-yl]phenoxy}-2-propanol as a colorless oil.

Provenance & Evidence