Dimethylamine → HCID 19423875, compound

HRID 743235Notes

Reaction equation

HRID 743235 reaction equation
[CH3:1][CH:2]([CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[CH2:3][CH2:4][C:5]1[CH:15]=[CH:14][CH:13]=[CH:12][C:6]=1[O:7][CH2:8][CH:9]1[CH2:11][O:10]1.[CH3:23][NH:24][CH3:25]>O1CCCC1>[CH3:23][N:24]([CH3:25])[CH2:11][CH:9]([OH:10])[CH2:8][O:7][C:6]1[CH:12]=[CH:13][CH:14]=[CH:15][C:5]=1[CH2:4][CH2:3][CH:2]([CH3:1])[CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 674DimethylamineHCID 19424021HCID 19424021, compound

Product 1

HCID 19423875HCID 19423875, compoundYield 86%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following a procedure similar to that described in Example 1(b), 1.0 g of 2-[2-(3-methyl-4-phenylbutyl)phenoxymethyl]oxirane [prepared as described in step (a) above] dissolved in 20 ml of tetrahydrofuran was treated with 4 ml of 50% by volume aqueous dimethylamine. The crude product was purified as described in Example 1(b), to give 0.99 g (yield 86%) of the title compound as a colorless oil.

Workup

  1. customThe crude product was purified

Sources & evidence

ORD record
ord-c62bee0de9c248bfaa77a5916e78f893
Source dataset
uspto-grants-1996_09
Patent number
US05556864

Reaction notes

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