2-(2-(3-Methoxyphenyl)ethyl)phenol → Potassium 2-[2-(3-methoxyphenyl)ethyl]phenolate

HRID 743244Notes

Reaction equation

HRID 743244 reaction equation
CC(C)([O-])C.[K+:6].[CH3:7][O:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[OH:23])[CH:12]=[CH:13][CH:14]=1>CC(N(C)C)=O>[CH3:7][O:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[O-:23])[CH:12]=[CH:13][CH:14]=1.[K+:6]

Participants

4

Reactant 2

HCID 105854482-(2-(3-Methoxyphenyl)ethyl)phenolHCID 23665647Potassium tert-butoxide

Product 1

HCID 23698896Potassium 2-[2-(3-methoxyphenyl)ethyl]phenolate

Reagents, catalysts & solvents 1

HCID 31374DimethylacetamideSolvent

Procedure

9.83 g of potassium t-butoxide were added, whilst ice-cooling and stirring, to a solution of 20.0 g of 2-[2-(3-methoxyphenyl)ethyl]phenol (prepared as described in Preparation 20) in 50 ml of dimethylacetamide, and the resulting mixture was stirred at the same temperature for 30 minutes, to give potassium 2-[2-(3-methoxyphenyl)ethyl]phenolate.

Workup

  1. temperaturecooling

Sources & evidence

ORD record
ord-ace70d24f700402b8a7b86845c571d2b
Source dataset
uspto-grants-1996_09
Patent number
US05556864

Reaction notes

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