Hydrochloric Acid → HCID 57497639, compound

Participants

Reaction Steps

1 ml of a 4N solution of hydrogen chloride in dioxane was added to a solution of 1.04 g of (S)-2-{2-[2-(3-methoxyphenyl)ethyl]phenoxymethyl}-4-methylmorpholine [prepared as described in step (a) above] in 20 ml of ethyl acetate, and the resulting mixture was allowed to stand at room temperature. The crystals which precipitated were collected by filtration and dried in vacuo, to give 1.05 g (yield 91%) of the title compound as colorless crystals, melting at 186°-187° C.

Provenance & Evidence