Hydrochloric Acid → HCID 57497645, compound

Participants

Reaction Steps

1.00 g of 2-(2-{2-[4-(3,5-dimethoxyphenyl)butyl]phenoxy}ethyl)-1-methylpyrrolidine [prepared as described in step (a) above] was dissolved in 10 ml of dioxane, and 0.8 ml of a 4N solution of hydrogen chloride in dioxane was added to the resulting solution. The mixture was stirred and then concentrated by evaporation under reduced pressure. A suitable amount of pentane was added to the concentrate and the mixture was agitated. The upper pentane layer was removed and the resulting oil was dried in vacuo, to give 1.09 g (a quantitative yield) of the title compound, as an oil.

Provenance & Evidence