Hydrochloric Acid → HCID 19423982, compound

Participants

Reaction Steps

0.311 g of 2-(2-{2-[2-(2-fluorophenyl)ethyl]phenoxy}ethyl)-1-methylpyrrolidine [prepared as described in step (a) above] was dissolved in 10 ml of ethyl acetate, and 0.36 ml of a 4N solution of hydrogen chloride in dioxane was added to the solution. The mixture was then allowed to stand at room temperature, and the crystals which precipitated were collected by filtration and dried in vacuo, to give 0.290 g (yield 84%) of the title compound as colorless crystals, melting at 178°-180° C.

Provenance & Evidence