Sulfuric acid magnesium salt (1:1) → HCID 70086218, compound

Participants

Reaction Steps

To a suspension of magnesium sulfate (150 g) and 1-methylphenylmethylamine (37.87 g, 32.9 mmol) in methylene chloride was added dropwise a solution of ethyl glyoxylate (33.55 g; 32.9 mmol) in methylene chloride, and the mixture was stirred at room temperature for 2 hours. The mixture was filtered, the filtrate was concentrated in vacuo to afford 67.5 g (quantitative) of N-[(1-methyl)phenylmethyl]imino-acetic acid ethyl ester, as an oil.

Provenance & Evidence