反应详情

Bromoacetyl-5-amino-1,10-phenanthroline (4) (Preparation 3; 1.00 g; 3.15 mmol) was dissolved in 50 ml dimethylformamide. Into this solution, was added 0.2 ml concentrated ammonia. The reaction mixture was stirred 1 hr. in the dark. The volume of the reaction mixture then was reduced to 2 ml by evaporation, and the product then was precipitated by addition of 2 ml of ice-cold deionized water. The resulting precipitate was collected by vacuum filtration, was washed with 20 ml ice-cold deionized water, and was washed with 50 ml acetonitrile. Yield: 0.45 g, 32%.

1. customThe volume of the reaction mixture then was reduced to 2 ml by evaporation
2. customthe product then was precipitated by addition of 2 ml of ice-cold
3. filtrationThe resulting precipitate was collected by vacuum filtration
4. washwas washed with 20 ml ice-cold
5. washwas washed with 50 ml acetonitrile