Ammonia → HCID 19424584, compound

Participants

Reaction Steps

(Iodoacetyl-glycyl)-5-amino-1,10-phenanthroline (6) (Preparation 5; 32.3 mg; 77.0 μmol) was dissolved in 2 ml dimethylformamide. Into this solution, was added 10 ml concentrated ammonia. The reaction mixture was stirred for 1 hr. in the dark, and then was evaporated under vacuum. The crude product was purified by preparative thin layer chromatography (silica; 2000 μm; ammonia:95% ethanol, 1:20, v/v). Yield: 10.5 mg, 44%.

Provenance & Evidence