HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 1-(Diphenylmethyl)-N-methylazetidin-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1-(Diphenylmethyl)azetidin-3-yl methanesulfonate | HCID 2758716 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(Diphenylmethyl)-N-methylazetidin-3-amine | HCID 50319 | 67.9% |
Reaction Steps
1-Benzhydryl-3-(methylamino)azetidine was prepared under the conditions of Example 9, but starting with 50 g of 1-benzhydryl-3-(methanesulphonyloxy)-azetidine and 48.9 g of methylamine in 250 cm3 of methanol. 27 g of 1-benzhydryl-3-(methylamino)azetidine are obtained in the form of a colorless solid, melting point 75° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05556861 |
| Source dataset | uspto-grants-1996_09 |
| ORD ID | ord-a5d9d18420604078a9804d62c30246f3 |
| Source note | uspto-grants-1996_09 |