Hydrochloric Acid → HCID 19421435, compound

HRID 744004Notes

Reaction equation

HRID 744004 reaction equation
C([O:3][C:4]([CH2:6][CH2:7][C:8]1[N:12]2[C:13]3[C:18]([NH:19][C:20](=[O:21])[C:11]2=[N:10][N:9]=1)=[CH:17][C:16]([N+:22]([O-:24])=[O:23])=[CH:15][CH:14]=3)=[O:5])C.[OH-].[Na+].Cl>O>[C:4]([CH2:6][CH2:7][C:8]1[N:12]2[C:13]3[C:18]([NH:19][C:20](=[O:21])[C:11]2=[N:10][N:9]=1)=[CH:17][C:16]([N+:22]([O-:24])=[O:23])=[CH:15][CH:14]=3)([OH:5])=[O:3]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 19421415HCID 19421415, compound

Product 1

HCID 19421435HCID 19421435, compoundYield 92.3%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.5 g (~1.5 mmol) of 1-(2-ethoxycarbonylethyl)-7-nitro[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one was added to a mixture of 50 ml of water and 1.5 ml of 2N sodium hydroxide. Stirring was continued for 24 h at 25° C. Addition of 4N hydrochloric acid to pH=2-3 gave the title compound (0.42 g; 92%) as a precipitate. M.p.>300° C. decomp.

Sources & evidence

ORD record
ord-dd91c4d63ae54c8898384286aea71d81
Source dataset
uspto-grants-1996_09
Patent number
US05559106

Reaction notes

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