Trifluoroacetic acid → HCID 19421452, compound

Participants

Reaction Steps

This compound was prepared by the procedure described in example 18 starting from 4-fluoro-3-nitrobenzotrifluoride and 2,4-dimethoxybenzylamine, except that the intermediate 1-[(diethoxyphosphoryl)methyl]-5-(2,4-dimethoxybenzyl)-8-trifluoromethyl[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one was deprotected by treatment with trifluoroacetic acid at room temperature overnight. The mixture was evaporated to dryness and the residue was recrystallized from ethanol to give the pure title compound, m.p. 204°-208° C.

Provenance & Evidence