反应详情

100 g of manganese dioxide is added in portions to a solution of 20 g of 6-(diphenyl-tert-butylsilyloxymethyl)-2-hydroxymethylpyridine in 236 ml of toluene at 24° C. under nitrogen and stirred for 24 hours. It is filtered on Celite, rewashed well with toluene and concentrated by evaporation in a vacuum. 19.0 g of the title compound is obtained as colored liquid, which is further used without further purification.

1. filtrationIt is filtered on Celite
2. concentrationconcentrated by evaporation in a vacuum