反应详情

7.7 g of 3-hydroxy-4-methoxy-benzyl alcohol, 10.35 g of potassium carbonate and 12.1 g of 1-bromo-3-methoxy-propane are stirred under reflux in 150 ml of acetone for 3 days. After evaporation of the solvent, water is added to the residue and extraction is carried out with ethyl acetate. After evaporation of the solvent the title compound is obtained from the organic extracts by means of FC (240 g of silica gel, dichloromethane/methanol=96:4): Rf (ethyl acetate/hexane=2:1)=0.31.

1. customAfter evaporation of the solvent, water
2. additionis added to the residue and extraction
3. customAfter evaporation of the solvent the title compound
4. customis obtained from the organic extracts by means of FC (240 g of silica gel, dichloromethane/methanol=96:4)