HCID 13120655, compound → HCID 13120656, compound

Participants

Reaction Steps

23.4 g (0.1 mol) of 3-(3,4-dimethoxyphenyl)-5,6-dihydro-2(1H)-pyrazinone are dissolved in 230 ml of ethanol and hydrogenated, in the presence of Raney nickel as the catalyst, at 40° to 60° C. and under a hydrogen pressure of 50 bar until saturation is reached. The catalyst is then filtered off, the filtrate is evaporated in vacuo and the residue is triturated with ether.

Provenance & Evidence