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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 745237Generated: October 30, 2026

Methyl formate → 1-Piperazinecarboxaldehyde, 2-(1H-indol-3-yl)-3-oxo-

https://huagongshe.com/reaction/745237

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl formateHCID 7865—
Reactant3-(1H-Indol-3-yl)-2-piperazinoneHCID 13120695—
Product1-Piperazinecarboxaldehyde, 2-(1H-indol-3-yl)-3-oxo-HCID 3070024—

Reaction Steps

21.5 g (0.1 mol) of 3-(3-indolyl)-piperazin-2-one (Example 30) are formylated with methylformate, as described in Example 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04598079
Source datasetuspto-grants-1986_07
ORD IDord-b21fb15113c84d0bac1464c888437a17
Source noteuspto-grants-1986_07