反应详情

5.75 g (37.0 mmol) 2-methyl-2-thiophene-3-yl-propylamine and 3.61 mL (44.4 mmol) formaldehyde were stirred overnight at RT together with 2.0 g molecular sieve (4 Å powder). The reaction mixture was filtered and the filtrate was concentrated to dryness by rotary evaporation.

1. filtrationThe reaction mixture was filtered
2. concentrationthe filtrate was concentrated to dryness by rotary evaporation