反应详情

3.0 g (20 mmol) 5-fluoro-1,3-dihydro-indol-2-one were stirred with 2.0 g Raney nickel in 50 mL methanol for 1.5 h at 200° C. in an autoclave. The catalyst was filtered off and the filtrate was concentrated to dryness by rotary evaporation. The residue was recrystallised from methanol, suction filtered and dried.

1. filtrationThe catalyst was filtered off
2. concentrationthe filtrate was concentrated to dryness by rotary evaporation
3. customThe residue was recrystallised from methanol, suction
4. filtrationfiltered
5. customdried