反应详情

Reflux 105.28 g (0.28 mole) 1-(4-chlorophenyl)-2-[(3-oxo-1-azabicyclo[2.2.2]oct-2-yl)methyl]-1,3-butanedione hydrochloride in 500 ml concentrated hydrochloric acid for 5 hours. Stir with mechanical stirrer. Chill the reaction mixture in an ice bath and collect the title compound via filtration.

1. temperatureChill the reaction mixture in an ice bath
2. customcollect the title compound
3. filtrationvia filtration