Hydrochloric Acid → HCID 13971534, compound

HRID 745560Notes

Reaction equation

Cl.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([C:9](=[O:24])[CH:10]([CH2:14][CH:15]2[C:20](=[O:21])[CH:19]3[CH2:22][CH2:23][N:16]2[CH2:17][CH2:18]3)C(=O)C)=[CH:5][C:4]=1[N+:25]([O-:27])=[O:26].Cl>>[ClH:2].[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([C:9](=[O:24])[CH2:10][CH2:14][CH:15]2[C:20](=[O:21])[CH:19]3[CH2:22][CH2:23][N:16]2[CH2:17][CH2:18]3)=[CH:5][C:4]=1[N+:25]([O-:27])=[O:26]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 23313755HCID 23313755, compound

Product 1

HCID 13971534HCID 13971534, compound

Procedure

In a manner similar to Example XXVI react 1-(4-chloro-3-nitrophenyl)-2-[(3-oxo-1-azabicyclo[2.2.2]oct-2-yl)methyl]-1,3-butanedione hydrochloride in refluxing concentrated hydrochloric acid to afford the title compound.

Sources & evidence

ORD record: ord-8f0c313cac4044aa8c408909f5dd95a4
Source dataset: uspto-grants-1986_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04599344

Reaction notes

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