1,12-Dodecanediamine → N-(12-aminododecyl)-aminomethanephosphonic acid monohydrate

HRID 745719Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 745719
Cl[CH2:2][P:3]([OH:6])(=[O:5])[OH:4].[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][NH2:20]>O>[OH2:4].[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][NH:20][CH2:2][P:3]([OH:6])(=[O:5])[OH:4]

Komponenten

4

Edukt 2

HCID 177271,12-DodecanediamineHCID 75723P-(Chloromethyl)phosphonic acid

Produkt 1

HCID 86740898N-(12-aminododecyl)-aminomethanephosphonic acid monohydrate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

Chloromethanephosphonic acid (15.1 g, 115.7 mmoles) and 1,12-diaminododecane (100 g, 0.5 moles) were heated under reflux in water (160 cm3) for 20 hours. The water was then distilled off and ethanol (250 cm3) was added. The phosphonic acid was filtered off and dried. The crude yield was 30.7 g (85%). A sample was purified by recrystallization from water/ethanol to give N-(12-aminododecyl)-aminomethanephosphonic acid monohydrate as a fine white crystalline solid having a melting point of 234° C.

Aufarbeitung

  1. distillationThe water was then distilled off
  2. additionethanol (250 cm3) was added
  3. filtrationThe phosphonic acid was filtered off
  4. customdried
  5. customA sample was purified by recrystallization from water/ethanol

Quellen und Nachweise

ORD-Eintrag
ord-391838f6d7db442d93fdeab565fc32e0
Quelldatensatz
uspto-grants-1986_07
Patentnummer
US04600429

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