反应详情

3.0 g (20 mmol) 5-fluoro-1,3-dihydro-indol-2-one, 50 mL methanol and 2.0 g Raney nickel were stirred for 1.5 h at 200° C. in an autoclave. After the catalyst had been filtered off the mother liquor was evaporated down and the residue was recrystallised from methanol.

1. filtrationAfter the catalyst had been filtered off the mother liquor
2. customwas evaporated down
3. customthe residue was recrystallised from methanol