Hydrochloric Acid → HCID 23312054, compound

Participants

Reaction Steps

21.9 g (0.05 mole) of ethyl 5-chloro-6-(3,5-dichlorophenylsulfonyl)-1,3-benzodioxole-2-carboxylate are covered with 75 ml of 2-n sodium hydroxide solution and the batch is heated for 1 hour in a boiling water bath, cooled, acidified with hydrochloric acid and then extracted with ethyl acetate. The extract is concentrated by evaporation, affording 5-chloro-6-(3,5-dichlorophenylsulfonyl)-1,3-benzodioxole-2-carboxylic acid. Melting point 166°-169° C. (crystallisation from ethyl acetate/toluene).

Provenance & Evidence