Hydrochloric Acid → HCID 23312054, compound

HRID 745810Notes

Reaction equation

HRID 745810 reaction equation
[Cl:1][C:2]1[C:15]([S:16]([C:19]2[CH:24]=[C:23]([Cl:25])[CH:22]=[C:21]([Cl:26])[CH:20]=2)(=[O:18])=[O:17])=[CH:14][C:5]2[O:6][CH:7]([C:9]([O:11]CC)=[O:10])[O:8][C:4]=2[CH:3]=1.[OH-].[Na+].Cl>>[Cl:1][C:2]1[C:15]([S:16]([C:19]2[CH:24]=[C:23]([Cl:25])[CH:22]=[C:21]([Cl:26])[CH:20]=2)(=[O:18])=[O:17])=[CH:14][C:5]2[O:6][CH:7]([C:9]([OH:11])=[O:10])[O:8][C:4]=2[CH:3]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 23312057HCID 23312057, compound

Product 1

HCID 23312054HCID 23312054, compound

Procedure

21.9 g (0.05 mole) of ethyl 5-chloro-6-(3,5-dichlorophenylsulfonyl)-1,3-benzodioxole-2-carboxylate are covered with 75 ml of 2-n sodium hydroxide solution and the batch is heated for 1 hour in a boiling water bath, cooled, acidified with hydrochloric acid and then extracted with ethyl acetate. The extract is concentrated by evaporation, affording 5-chloro-6-(3,5-dichlorophenylsulfonyl)-1,3-benzodioxole-2-carboxylic acid. Melting point 166°-169° C. (crystallisation from ethyl acetate/toluene).

Workup

  1. temperaturethe batch is heated for 1 hour in a boiling water bath
  2. temperaturecooled
  3. extractionextracted with ethyl acetate
  4. concentrationThe extract is concentrated by evaporation

Sources & evidence

ORD record
ord-e5e6f20b845c4e7781aa100ad0f0e112
Source dataset
uspto-grants-1986_07
Patent number
US04600709

Reaction notes

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