Sodium Carbonate → HCID 13375748, compound

HRID 745859Notes

Reaction equation

HRID 745859 reaction equation
C[O:2][C:3]([C:5]1[CH:25]=[CH:24][C:8]([C:9]2[O:10][C:11]3[C:16]([C:17](=[O:19])[CH:18]=2)=[CH:15][CH:14]=[C:13]([NH:20][C:21](=[O:23])[CH3:22])[CH:12]=3)=[CH:7][CH:6]=1)=[O:4].C(=O)([O-])[O-].[Na+].[Na+]>O1CCOCC1.O>[C:21]([NH:20][C:13]1[CH:12]=[C:11]2[C:16]([C:17](=[O:19])[CH:18]=[C:9]([C:8]3[CH:24]=[CH:25][C:5]([C:3]([OH:4])=[O:2])=[CH:6][CH:7]=3)[O:10]2)=[CH:15][CH:14]=1)(=[O:23])[CH3:22]

Participants

5

Reactant 2

HCID 10340Sodium CarbonateHCID 13375747HCID 13375747, compound

Product 1

HCID 13375748HCID 13375748, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 312751,4-DioxaneSolvent

Conditions

Temperature
100 °C

Procedure

6 g of 7-acetamido-4'-flavonecarboxylic acid methyl ester are dissolved in 600 cc of dioxane. 12 g of sodium carbonate, dissolved in 250 cc of water, are added and the mixture is heated at 100° C. with stirring until the reaction is complete, for about 8 hours. The reaction is checked by plate chromatography (benzene (90)-dioxane (25)-acetic acid (4) elution solvent).

Workup

  1. additionare added
  2. washThe reaction is checked by plate chromatography (benzene (90)-dioxane (25)-acetic acid (4) elution solvent)

Sources & evidence

ORD record
ord-5319e8221002439391d953dcfe835237
Source dataset
uspto-grants-1986_07
Patent number
US04600788

Reaction notes

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