Hydrochloric Acid → HCID 178478602, compound

HRID 745878Notes

Reaction equation

HRID 745878 reaction equation
[NH2:1][C:2]1[C:6]([NH:7][CH2:8][CH2:9][CH2:10][O:11][C:12]2[CH:17]=[C:16]([CH2:18][N:19]3[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]3)[CH:15]=[CH:14][N:13]=2)=[N:5]S(=O)[N:3]=1.[ClH:26]>CO>[ClH:26].[ClH:26].[ClH:26].[N:19]1([CH2:18][C:16]2[CH:15]=[CH:14][N:13]=[C:12]([O:11][CH2:10][CH2:9][CH2:8][NH:7][C:6](=[NH:5])[C:2](=[NH:1])[NH2:3])[CH:17]=2)[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 159613413-Amino-4-[3-(4-piperidinomethyl-2-pyridyloxy)propylamino]-1,2,5-thiadiazole 1-oxide

Product 1

HCID 178478602HCID 178478602, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of Step B (5.0 g; 13.7 mmoles) was dissolved in 80 ml of methanol and treated with 9.1 ml of concentrated HCl. After stirring at ambient tempeature for 4.5 hours, the solution was evaporated to dryness under reduced pressure to give the title compound.

Workup

  1. customthe solution was evaporated to dryness under reduced pressure

Sources & evidence

ORD record
ord-47437bf499cf4da891b48125c05ef239
Source dataset
uspto-grants-1986_07
Patent number
US04600779

Reaction notes

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