反应详情

A mixture of 2,3,5-trichlorobenzoic acid (90 g, 0.4M) and dimethylformamide (1 ml) in thionyl chloride (200 ml) was heated to reflux for 2 hours. The cooled solution was evaporated down in vacuo and the residue distilled under nitrogen. Yield 89.2 g (90%), b.p. 158°-160° C. at the pressure of 30 mm of mercury.

1. temperaturewas heated
2. temperatureto reflux for 2 hours
3. customThe cooled solution was evaporated down in vacuo
4. distillationthe residue distilled under nitrogen