Methylamine → HCID 23311193, compound

HRID 745932Notes

Reaction equation

HRID 745932 reaction equation
[CH2:1]([CH:4]1[C:8]2[CH:9]=[N:10][C:11]([CH2:21]Cl)=[C:12]([O:13]CC3C=CC=CC=3)[C:7]=2[CH2:6][O:5]1)[CH2:2][CH3:3].[CH3:23][NH2:24]>C1C=CC=CC=1>[CH2:1]([CH:4]1[C:8]2[CH:9]=[N:10][C:11]([CH2:21][NH:24][CH3:23])=[C:12]([OH:13])[C:7]=2[CH2:6][O:5]1)[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 23311188HCID 23311188, compound

Product 1

HCID 23311193HCID 23311193, compoundYield 66%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

The method of example 1 was repeated, but starting with 1,3-dihydro-3-propyl-6-chloromethyl-7-benzoxy-furo-(3,4-c)-pyridine and gaseous methylamine dissolved in benzene. Yield 66% of an oily product, elemental analysis of which showed good correspondence with the formula C12H18N2O2.HCl.

Sources & evidence

ORD record
ord-f5024f143b424a9ea5f4fee9725ddc7f
Source dataset
uspto-grants-1986_07
Patent number
US04602020

Reaction notes

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