Sodium Bicarbonate → 1-(1,2,3,4-Tetrahydronaphthalen-2-yl)imidazole

HRID 745977Notes

Reaction equation

Cl.[N:2]1([CH:7]2[CH2:16][CH2:15][C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[CH2:8]2)[CH:6]=[CH:5][N:4]=[CH:3]1.C([O-])(O)=O.[Na+]>>[N:2]1([CH:7]2[CH2:16][CH2:15][C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[CH2:8]2)[CH:6]=[CH:5][N:4]=[CH:3]1

Participants

Reactant 2

HCID 516892Sodium Bicarbonate

HCID 233112301,2,3,4-Tetrahydro-2-(1-imidazolyl)-naphthalene hydrochloride

Product 1

HCID 132878261-(1,2,3,4-Tetrahydronaphthalen-2-yl)imidazole

Procedure

1,2,3,4-tetrahydro-2-(1-imidazolyl)-naphthalene hydrochloride, which treated with the stoichiometric amount of NaHCO3, gave 1,2,3,4-tetrahydro-2-(1-imidazolyl)naphthalene, m.p. 95°-98° C.

Sources & evidence

ORD record: ord-e543b400e5d04f6b87811d01005d3a1a
Source dataset: uspto-grants-1986_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04602022

Reaction notes

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