Hydrogen Bromide → HCID 178430867, compound

Participants

Reaction Steps

A mixture of 2-(p-methoxyphenylmethyl)-4-methylimidazole (5.0 g, 0.025 m), glacial acetic acid (37 mL) and 48% hydrobromic acid (125 ml) was heated at reflux for 5 hours. The solution was concentrated under reduced pressure and the oily residue was stirred in saturated sodium bicarbonate solution (55 mL) for 17 hours. The solid was collected and dried to yield 4.22 g (90%) of II; m.p. 193°-194° C. (CH3CN).

Provenance & Evidence