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HRID746194

反应详情

EQUATION

反应方程式

HRID 746194 的结构方程式

REACTANTS

反应物

2
结构：COC(C)(N)CO
HCID20240818

未命名化合物

结构：CC(C)(C)OC(=O)[O-].CC(C)(C)OC(=O)[O-]
HCID52911111

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(CO)NC(=O)OC(C)(C)C
HCID14578673

tert-Butyl (1-hydroxy-2-methylpropan-2-yl)carbamate

C9H19NO3

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CC(C)(C)O
溶剂HCID6386

tert-Butyl alcohol

C4H10O

结构：O=C([O-])O.[Na+]
溶剂HCID516892

Sodium Bicarbonate

CHNaO3

PROCEDURE

实验过程

2-Methoxy-2-amino-1-propanol is dissolved in saturated aqueous NaHCO3 at room temperature. Di-tert-butyl di-carbonate is added in tert-butanol. The contents are stirred overnight and then extracted with ethyl acetate. The organic layer is dried over MgSO4 and filtered. The filtrate is evaporated to give N-Boc-2-amino-2-methyl-1-propanol.

WORKUP

后处理

  1. extractionextracted with ethyl acetate
  2. dry with materialThe organic layer is dried over MgSO4
  3. filtrationfiltered
  4. customThe filtrate is evaporated