HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromoethanol → 2-(4-Phenylpiperidino)ethyl acetoacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromoethanol | HCID 10898 | — |
| Reactant | Diketene | HCID 12661 | — |
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reactant | 2-(4-Phenylpiperidin-1-yl)ethanol | HCID 264832 | — |
| Product | 2-(4-Phenylpiperidino)ethyl acetoacetate | HCID 13861153 | — |
Reaction Steps
4-Phenylpiperidine was reacted with ethylene bromohydrin in the same manner as Reference Example 5, and the resulting oily 4-phenyl-1-piperidineethanol was further reacted with diketene to give 2-(4-phenylpiperidino)ethyl acetoacetate as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04603135 |
| Source dataset | uspto-grants-1986_07 |
| ORD ID | ord-8d3d22bca60842e7a6f06068cd037bbb |
| Source note | uspto-grants-1986_07 |