反应详情

An aqueous solution (1 mL) of (NH4)2Ce(NO3)6 (0.035 g, 0.064 mmol) was added dropwise to a THF solution (5 mL) of 4a (0.029 g, 0.032 mmol). The reaction mixture immediately turned deep red. After 6 h the reaction mixture was poured into ether and washed with a saturated solution of NaHCO3 and water. The organic layer was dried with MgSO4 and the solvent removed under reduced pressure. The crude product was purified by column chromatography on silica gel (1:1 CH2Cl2/hexane) to afford 5a as a deep red solid in 80% yield (mp 86-87° C.).

1. washwashed with a saturated solution of NaHCO3 and water
2. dry with materialThe organic layer was dried with MgSO4
3. customthe solvent removed under reduced pressure
4. customThe crude product was purified by column chromatography on silica gel (1:1 CH2Cl2/hexane)