HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → N-(2-benzoylphenyl)-4-nitroBenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 4-Nitrobenzenesulfonyl chloride | HCID 7404 | — |
| Reactant | 2-Aminobenzophenone | HCID 76080 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(2-benzoylphenyl)-4-nitroBenzenesulfonamide | HCID 10474997 | — |
Reaction Steps
2-Aminobenzophenone (20 mg) was dissolved in 1 mL of methylene chloride and 4-nitrobenzenesulfonyl chloride (34 mg, 1.5 equiv) was added thereto followed by pyridine (16 mL, 2 equiv). After 10 minutes the reaction mixture was oncentrated in vacuo, subjected to flash chromatography (eluting with 0% to 25% EtOAc/hexane) to provide N-(2-benzoylphenyl)-4-nitrobenzenesulfonamide. ESMS, M+H+ found: 383.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07393873B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-751a4213bab7459286c4a7dd5c2c3649 |
| Source note | uspto-grants-2008_07 |