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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 747035Generated: October 26, 2026

4-Hydroxy-3,3-dimethyl-2-oxa-8-azaspiro[4.5]decane → HCID 86606929, compound

https://huagongshe.com/reaction/747035

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydroxy-3,3-dimethyl-2-oxa-8-azaspiro[4.5]decaneHCID 69147335—
Reactant(2R,3R,4R)-2-[(1R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)-tetrahydropyran-4-carbaldehydeHCID 86601740—
ProductHCID 86606929HCID 86606929—

Reaction Steps

This product was prepared according to the procedure described in Example 6 using (2R,3R,4R)-2-[(1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)-tetrahydropyran-4-carbaldehyde (Description 11) and 4-hydroxy-3,3-dimethyl-2-oxa-8-azaspiro[4.5]decane (Description 21).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07393858B2
Source datasetuspto-grants-2008_07
ORD IDord-846462ac8fc04eee9291ebf90f4f1ded
Source noteuspto-grants-2008_07