HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Amino-4-methyl-2-quinolinone → HCID 178429270, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Amino-4-methyl-2-quinolinone | HCID 88277 | — |
| Reactant | 4-Chloro-6-(4-(trifluoromethyl)phenyl)pyrimidine | HCID 16747837 | — |
| Product | HCID 178429270 | HCID 178429270 | — |
Reaction Steps
Analogous to the procedure used to prepare Example 5(b), 4-chloro-6-(4-trifluoromethylphenyl)pyrimidine, Example 5(a), (150 mg, 0.58 mmol) and carbostyril 124 (50 mg, 0.29 mmol, Aldrich) afforded, after recrystallization from MeOH, the title product as bright-yellow crystals. MP: 373° C. (with decomposition). MS (ESI, pos. ion) m/z: 397 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07396831B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-574c49fe495d4af8921101c7445bbd72 |
| Source note | uspto-grants-2008_07 |