HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → [6-(1-Methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-pyrimidin-4-yl]-quinolin-7-yl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | Quinolin-7-yl-[6-(1,2,3,6-tetrahydro-pyridin-4-yl)-pyrimidin-4-yl)-amine | HCID 22135542 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | [6-(1-Methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-pyrimidin-4-yl]-quinolin-7-yl-amine | HCID 22135521 | — |
Reaction Steps
This compound could be prepared from quinolin-7-yl-[6-(1,2,3,6-tetrahydro-pyridin-4-yl)-pyrimidin-4-yl]-amine and formaldehyde in the presence of sodium triacetoxyborohydride and MeCN.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07396831B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-b169793700154b17a3bae14ec892bd41 |
| Source note | uspto-grants-2008_07 |