Norbornadiene → HCID 59749439, compound

Participants

Reaction Conditions

Reaction Steps

5-Azidomethyl-3-(4-bromo-phenyl)-4,5-dihydro-isoxazol (12.3 g, 43.6 mmol) and bicyclo[2.2.1]hepta-2,5-diene (23.6 ml, 218.1 mmol) were added to dioxane (200 ml), heated to 100° C. and stirred for six hours. The reaction mixture was concentrated in vacuo followed by addition of ethyl ether (200 ml). The precipitate was collected and washed with ethyl ether (3×20 ml) and dried under nitrogen to give the desired product (8.8 g).

Provenance & Evidence